No 03+04/2003 » Abstract

Comparison of Automated ACMIA and EMIT Immunoassays for Whole Blood Cyclosporin Monitoring

by Barbara Dessars, Frederic Cotton, Philippe Thiry and Beatrice Gulbis

Objective: Evaluation of a new fully automated antibody conjugated magnetic immunoassay (ACMIA) for whole blood cyclosporin (CsA) monitoring.
Method: Evaluation of the analytical performance of the ACMIA method and comparison to the Enzyme Multiplied Immunoassay (EMIT) method.
Results: The analytical performance of the ACMIA and the EMIT methods was comparable. Without the need of a pretreatment step of the sample, the ACMIA method is faster than the EMIT method.
Conclusion: The ACMIA method for CsA monitoring is a good alternative to the EMIT method.

Clin. Lab. 2003;49(3-4):135-140.

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