No 01+02/2007 » Abstract

Evaluation of the VITROS 5,1 FS Chemistry System in a Large Pediatric Laboratory

by Kurt Herkner, Rosmarie Reiter-Reisacher, Oswald Sonntag

The VITROS® 5,1 FS analytical system was evaluated. The measurement of the serum proteins and HDL cholesterol with the newly developed MicroTip technology was compared with other nephelometric and turbidimetric methods. The within-run imprecision for apolipoprotein A1, apolipoprotein B, complement 3, complement 4, transferrin, immunoglobulin A, immunoglobulin M, immunoglobulin G and HDL cholesterol showed coefficients of variation between 0.4% and 4.7%. The day-to-day imprecision showed coefficients of variation between 0.5% and 4.0%. The correlation with the comparative methods (nephelometric or turbidimetric) was good, with Pearson correlation coefficients of between 0.959 and 0.995. The comparison of apolipoprotein A1 showed a slope of about 0.76. An explanation for the difference could not be found. The VITROS 5,1 FS analytical system is a reliable routine instrument which fits into a large pediatric laboratory of a university.

Clin. Lab. 2007;53(1-2):17-26.

Buy Fulltext PDF Print Fri 18th May, 2012