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Abstract |
Non-Infectious Transfusion.Associated Reactions - Results of Retrospective Investigations Performed in a National Blood Transfusion Service between 1994 and 1996 Including the Results of the Investigations for Bacterial Contamination |
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From 1994 to 1996 we retrospectively investigated 917 cases of reported possible transfusion-associated noninfectious reactions involving 1123 blood products. In most cases the observed symptoms were not severe. Nevertheless, hemolysis was reported in 0.5%, anuria in 0.4%, icterus in 1% and shock in 6% of the cases. By retrospective investigation we found 2 cases (0.2%) of AB0 incompatibility caused by clerical error and 21 cases (2.3%) of unexpected antibodies against donor red blood cells reacting in vitro at 37°C or with AHG. No bacterial contamination was found. In more than half of the cases from 1995/96 we found HLA and/or thrombocyte antibodies. There was no possibility to draw a conclusion from the reported symptoms to the existence of relevant medical findings by the serological investigations. |
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