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A Case of Cutaneous Involvement in T Lymphoblastic Lymphoma Leukemia by Ling Zhang, Yunxin Zeng, Na Cheng, Xiaoyun Liu, Xiaoqing Li, Bing Long, Dongjun Lin

Background: Cutaneous involvement is more prevalent in B lymphoblastic lymphoma (B-LBL) than T lymphoblastic lymphoma (T-LBL). The authors describe a rare case of cutaneous involvement in a 25-year-old woman with T lymphoblastic lymphoma leukemia.
Methods: Hematologic investigation, bone marrow aspirate and biopsy, cytogenetic analysis and cutaneous lesion biopsy were performed.
Results: The patient achieved complete remission after induction therapy with the regimen of CHOEP + P, then received another CHOEP + P regimen. Unfortunately, the patient refused further treatment and was lost to follow-up.
Conclusions: Skin biopsy, immunohistochemistry of the skin lesions, bone marrow aspirate, and biopsy are important to confirm a diagnosis of T-LBL. Cutaneous involvement in T-LBL as a prognostic factor needs further studies.

DOI: 10.7754/Clin.Lab.2017.170222