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A Misdiagnosed Atypical Case of Diffuse Large B Cell Lymphoma Diagnosed by Computed Tomography Guided Spleen Biopsy by Liejun Jiang, Qiang Wei, Cheng Peng, Han Li, Endi Wang, Xiaomei Zhang, Huayi Huang

Background: Lymphoma is a malignancy of hematopoietic and lymphoid tissues. Early diagnosis of lymphoma is very important and could save patients’ lives. Nevertheless, the diagnosis of lymphoma could be difficult in the presence of complex manifestations and a lack of convincing laboratory findings. Here we report a case of large B cell lymphoma misdiagnosed as hemophagocytic syndrome during the hospitalization and treatment course.
Methods and Results: Retrospective review of patient’s clinical data, differential diagnosis, and treatment were performed. Patient’s disease course was followed and the final diagnosis, along with relevant discussions and summaries were documented.
Conclusions: This report may be helpful in the diagnosis of lymphoma with complex manifestations differentiated from hemophagocytic syndrome, and may facilitate early diagnosis and treatment.

DOI: 10.7754/Clin.Lab.2020.200640