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Abstract

A False Positive HIV Confirmatory Test Result in Pregnancy and its Impact on Patient Management and Outcome by Kamran Kadkhoda, Benito Alvarez, John Simeone, Hannah Guidosh

Background: HIV screening and diagnosis during pregnancy is routine and of paramount importance. False positive results are rare but may have catastrophic consequences on both mother’s and baby's health.
Methods: The patient was tested using HIV screening assay and HIV confirmatory assay as well as HIV proviral DNA and HIV plasma viral load test.
Results: Her HIV screen tests were very low positive. Her HIV confirmatory screen tested positive, indeterminate, and negative across multiple repetitions. Her proviral DNA and plasma HIV tests were both negative.
Conclusions: This report highlights a clear example and provides guidance as to how these scenarios should be handled.

DOI: 10.7754/Clin.Lab.2025.250651