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Background: Aim is to investigate the clinical value of an early coagulation test combined with complete blood count in differential diagnosis of pulmonary contusion and fracture in pediatric patients.
Methods: A cross-sectional study was conducted. A total of 35 children hospitalized with lung contusion from Jan-uary 2018 to April 2021 at Anhui Children's Hospital were randomly selected and assigned to the observation group. Accordingly, another 35 hospitalized children with fractures, from January 2018 to May 2021, were in-cluded in the control group. The results of an early coagulation test, including prothrombin time (PT), interna-tional normalized ratio (INR), activated partial thromboplastin time (APTT), fibrinogen concentration (FBG), thrombin time (TT), and D-dimer, and complete blood count, including hemoglobin (HB) and platelet (PLT) were obtained within the first three hours after admission. The clinical value of an early coagulation test combined with complete blood count in differential diagnosis of pulmonary contusion and fracture in pediatric patients was in-vestigated.
Results: The results showed that 94.28% of pediatric patients with lung contusion had higher D-dimer levels than the normal reference range, while 54.28% of pediatric patients with fractures had elevated D-dimer levels. The proportion of pediatric patients with lung contusion having elevated D-dimer levels was significantly higher than that of pediatric patients with fractures (p < 0.05). Additionally, the APTT of pediatric patients with lung contu-sion was lower than the normal reference value in 5 cases (14.28%), which was higher compared to pediatric pa-tients with fractures (p < 0.05). The proportion of HB lower than the normal reference range in children with pulmonary contusion was 68.57%, which was higher than that in children with fracture (p < 0.05).
Conclusions: The results of D-dimer and APTT in coagulation tests and HB level have certain value in the clinical differential diagnosis of early pediatric pulmonary contusion and fracture.
DOI: 10.7754/Clin.Lab.2025.250808
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